Glutamic acid decarboxylase antibodies in screening for autoimmune diabetes: influence of comorbidity, age, and sex on specificity and threshold values.

نویسندگان

  • M R Batstra
  • A van Driel
  • J S Petersen
  • C A van Donselaar
  • M J van Tol
  • G J Bruining
  • D E Grobbee
  • T Dyrberg
  • H J Aanstoot
چکیده

Severina ME, et al. Troponin I is released in bloodstream of patients with acute myocardial infarction not in free form but as complex. Clin Chem 1997;43:1379–85. 12. Giuliani I, Bertinchant J-P, Granier C, Laprade M, Chocron S, Toubin G, et al. Determination of cardiac troponin I forms in the blood of patients with acute myocardial infarction and patients receiving crystalloid or cold blood cardioplegia. Clin Chem 1999;45:213–22. 13. Bodor GS, Oakley AE, Allen PD, Crimmins DL, Ladenson JH, Anderson PAW. Troponin I phosphorylation in the normal and failing adult human heart. Circulation 1997;96:1495–500. 14. Ingraham RH, Hodges RS. Effects of Ca and subunit interaction on surface accessibility of cysteine residues of cardiac troponin. Biochemistry 1988;27:5891–8. 15. Dasgupta A, Chow L, Nazareno L, Tso G, Datta P. Analytical performance of a new chemiluminescent troponin I assay using ACS:180 analyzer. [Abstract] Clin Chem 1999;45:A136. 16. College of American Pathologists. Chemistry survey 1997: sets C3, C4, C5, C6, C7, and C8. Participant summary. Northfield, IL: College of American Pathologists, 1997. 17. Hegner N, Baum H, Eller T, Pohl KH, Messinger M, Mockel M, et al. Multicenter evaluation of OPUS troponin I compared to myoglobin and CK-MB concentrations in cardiac diseases. Clin Lab 1997;43:501–14. 18. Bhayana V, Gougoulias T, Gawad Y. A comparison of four serum cardiac troponin I methods [Abstract]. Clin Chem 1997;43:S128.

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T-cell Tolerance Following Bacterial Glutamic Acid Decarboxylase (GAD) Feeding in Streptozotocin-induced Diabetes

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Characteristics and Prevalence of Latent Autoimmune Diabetes in Adults (LADA) in Torbat-e Heydarieh, Iran

Background and Aims: The prevalence of latent autoimmune diabetes in adults (LADA) among diabetic patients is less recognized and underdiagnosed. The aim of this study was to determine the prevalence of LADA in type 2 diabetic patients and to compare the characteristics of these two groups in Torbat-e Heydarieh, Iran. Materials and Methods: Totally, 198 male and 277 female patients diagnosed ...

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Measurement of antibodies against glutamic acid decarboxylase 65 (GADA): two new 125I assays compared with [35S]GAD 65-ligand binding assay.

Recently, 65-kDa glutamic acid decarboxylase (GAD 65) antibodies (GADA) have been introduced as autoimmune markers in blood to confirm the diagnosis of insulin-dependent diabetes mellitus (IDDM). In this study, to evaluate two new assays that use 125I-labeled GAD 65, we assayed samples from 100 children with recent onset of diabetes and 100 control children, the results were compared with those...

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عنوان ژورنال:
  • Clinical chemistry

دوره 45 12  شماره 

صفحات  -

تاریخ انتشار 1999